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A CONMEBOL Libertadores 2024 j� tem todos os 47 times definidos para
a pr�xima edi��o. Nesta segunda-feira (18), o Aurora,?? da Bol�via, foi o �ltimo clube a
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Pesquisadores estudaram dados gen�ticos de mais de 1 milh�o?? de pessoas que fazem consumo excessivo de �lcool habitualmente, incluindo indiv�duos com ancestralidades europeia, africana, latino-americana, asi�tica-oriental e sul-asi�tica.
A enorme?? amostra revelou que o consumo problem�tico de bebidas alco�licas pode estar atrelado a uma arquitetura gen�tica compartilhada. A pesquisa foi?? publicada em 7 de dezembro na revista
descobertas podem ajudar na compreens�o gen�tica do uso problem�tico de �lcool, "uma caracter�stica que?? combina transtorno por uso de bebida alco�lica e problemas relacionados ao �lcool avaliados por meio de um question�rio", segundo definem?? os cientistas.
O estudo � liderado por pesquisadores do VA Connecticut Healthcare Center da Escola de Medicina de Yale, nos Estados?? Unidos. A investiga��o se baseou em dados do Million Veteran Program (MVP), que foram combinados com informa��es de muitas outras
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"Aproveitando as informa��es de multiancestralidade, identificamos 110 regi�es gen�ticas e tivemos um mapeamento fino aprimorado das variantes causais potenciais?? em cada regi�o", disse o autor principal do estudo, Hang Zhou, professor assistente na Escola de Medicina de Yale, em?? comunicado.A pesquisa � a maior at� o momento para o uso problem�tico do �lcool, com muitos genes de risco descobertos.?? Os cientistas usaram v�rios m�todos, incluindo an�lises em 13 tecidos cerebrais e estudos da
de cromatina no c�rebro (um complexo de?? DNA, RNA e prote�nas).
de cor cromatina (uma crom�tica) (dois complexos de cromossomas) e de cromatinina no cerebrovascular.
"Um dos produtos mais?? importantes desta pesquisa � a informa��o fornecida sobre o risco de uso problem�tico do �lcool em todo o genoma", disse?? Joel Gelernter, autor s�nior do estudo. Ele afirma que os resultados permitiram at� mesmo sugerir alguns medicamentos j� aprovados que?? podem
polig�nico" (PRS, na sigla em ingl�s), possivelmente �teis para estimar o risco gen�tico de cada pessoa em consumir abusivamente �lcool.
Embora?? o PRS que os pesquisadores calcularam n�o esteja pronto para uso cl�nico, eles testaram os resultados em centenas de caracter�sticas?? m�dicas de v�rios biobancos norte-americanos, incluindo o Biobanco da Universidade Vanderbilt, BioMe do Mount Sinai, bioMe de Mounta Sinei,BioMe e?? BioBanco
etiologia gen�tica do consumo problem�tico de �lcool, e essas descobertas podem trazer uma poss�vel aplicabilidade cl�nica das percep��es gen�ticas, juntamente?? com a neuroci�ncia, a biologia e a ci�ncia de dados", conclu�ram os autores.
Pesquisadores apontam evid�ncias de transforma��es na plataforma continental?? australiana e como mudan�as no n�vel do mar afetaram seu povoamento
Pesquisa analisou como a preval�ncia de diabetes, hipertens�o e doen�a?? renal cr�nica tem rela��o com indicadores de racismo
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